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GREAT POINT PARTNERS LLC 13F portfolio summary

GREAT POINT PARTNERS LLC of GREAT POINT PARTNERS LLC has 42 current stock holdings with a reported portfolio value of $529.1M. The portfolio 1 year return is +166.66%. Top holdings include ABVX (5.15%), VERA (4.87%), ALMS (4.55%), DFTX (3.78%), ORKA (3.30%).

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GREAT POINT PARTNERS LLC

GREAT POINT PARTNERS LLC
Latest filing: 2026-06-30

GREAT POINT PARTNERS LLC runs GREAT POINT PARTNERS LLC and currently holds 42 stock positions, which is fewer than the average of 230 among the investors we track. The portfolio is valued at approximately $529.12M. Their top holdings are ABVX, VERA, ALMS, DFTX, ORKA. The top five represent 21.6% of reported portfolio weight. GREAT POINT PARTNERS LLC ranks #90 out of 1000 investors tracked by Alpha Score. In the most recent quarter, GREAT POINT PARTNERS LLC initiated 4 new positions. They added to 3 existing positions. They trimmed 2 positions. Their current best-performing preview position is ORKA with returns of +94.03%.

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Top 5 Holdings
ABVX5.1%
VERA4.9%
ALMS4.6%
DFTX3.8%
ORKA3.3%
Top 5: 21.6%
Portfolio Returns
1 Year
+166.66%
#22/1000
3 Year
+153.36%
#112/1000
5 Year
+146.98%
#119/1000

Portfolio Value

$529.12M

Alpha Score

139.3

#90 of 1000

Holdings

42

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42 stock holdings

HoldingWeightAvg BuyCurrentReturnQuarter Change
ABVX
ABIVAX SA
5.15%$133.26$114.95-13.74%
New Buy
VERA
VERA THERAPEUTICS INC
4.87%$42.02$32.28-23.19%
Added
+201.40%
ALMS
ALUMIS INC
4.55%$22.03$24.17+9.71%
Held
DFTX
DEFINIUM THERAPEUTICS INC
3.78%$47.04$44.91-4.53%
New Buy
ORKA
ORUKA THERAPEUTICS INC
3.30%$19.23$107.96+461.41%
Held
MLTX
MOONLAKE IMMUNOTHERAPEUTICS
3.15%$18.99$15.76-17.01%
Added
+71.16%
AMLX
AMYLYX PHARMACEUTICALS INC
2.38%$4.05$38.66+854.57%
Trimmed
-60.00%
NKTR
NEKTAR THERAPEUTICS
2.31%$61.93$74.02+19.52%
Trimmed
-44.70%
LBRX
LB PHARMACEUTICALS INC
1.95%$25.08$47.62+89.87%
Added
+5.74%
RLMD
RELMADA THERAPEUTICS INC
1.10%$6.96$4.63-33.48%
Held

Showing 1-10 of 42